Skip to main content

GMP1 Difference between Static Pass Box AND Dynamic Pass Box


Pass Box is used to pharma sectors.It is used to transfer or pass material between two areas.
The area must be same class or different class. Their are different room classification like ISO1 to ISO9 and WHO A, B, C, D.
The box transfer lower level cleanliness to high level cleanliness or vice-versa.
It is made of 304 Stainless steel (Pass box).

Two type of pass box give 1) Static Pass Box, 2) Dynamic Pass Box

Static Pass Box
     
1) Static Pass Box is transfer  material which is equally clean.
2) High possibility, there are pressure is Equal. (Both Room)
3) Electromagnet interlock system arrange both side of the door. It is help to                                              only indicate, door are open or close with the help of LED light.
4) Its both doors are open at a time. Their no feature to interlock both doors.
5) Static Pass Box is 8 watts.
6) Fluorescent lamp is 40 watts.
7) The Static Pass Box do not have filters.
8) No required gauge by same classification rooms.

Dynamic Pass Box

1) Dynamic Pass Box is transfer material which unequal pressure.
2) There are less possibility or no pressure is Equal. (Both Room)
3) Electromagnet interlock system arrange both side of the door.
     This is help to protects for outside contamination particles.
4) Their are interlock Guard which is control inlet and outlet doors.
     Once doors is open then other remains close and vice versa.
5) Dynamic Pass Box is 8 watts.
6)  Fluorescent lamp is 20 watts.
7) Dynamic Pass Box uses to type of filters 0.3 (HEPA filter) and 10 (PRE                                               filter) as per requirement.
8) It also has a Pressure guage, range between 0 to 25 mmWC.
    It has fitted blower 0.5 hp to pass through out dust particles.

Comments

  1. Vey informative article. Really helpfull. Thnax Manav.

    ReplyDelete

Post a Comment

Popular posts from this blog

GMP5 Dead Leg calculation

Shown picture, if D=25mm & distance X is greater than 50mm, we have a dead leg that is too long. Long dead leg is helpful to growth microorganisms. Long dead leg means to store excess water (WFI, PW etc). Long Dead leg does not circulate the water, hence it always short. Dead leg is not more than 1.5D of the pipe line. A Dead leg system can obtain than this type of problem created Fluid pooling, Reduced Cleasnability, Difficult sterilization. Hence dead leg always short.

GMP6 PW & WFI

PW:- Purified water  is  water  that comes from any source, but has been  purified  to remove any chemicals or contaminants. Its  has been mechanically filtered or processed to remove impurities and make it suitable for use. Types of  purification  include distillation, Capacities de-ionization, microfiltration, ultrafiltration reverse osmosis (RO), and carbon filtration. It's from an underground source and may or may not have been treated and  purified . PW is used in Non-Parental drugs. WFI:- It is water that is intended for use in the manufacture of medicines for parenteral administration whose solvent is water (WFI in bulk), or water that is used to dissolve or dilute substances or preparations for parenteral administration (heat- sterilised WFI) PW is treat convert  WFI is used in Parental Drugs. WFI is water of extra high quality without contamination.  The United States Pharmacopeia (USP) defines as highly pu...

GMP4 Pharmaceutical company used 2 type of Diffuser in clean room.

Pharmaceutical company used 2 type of Diffuser in clean room. 1) Perforated Plate Diffuser. 2) Swirl Diffuser. 1) Perforated Plate Diffuser.:-      WHO permit or recommended diffuser used to pharma company. This type of diffuser use to air pass laminar flow. Diffuser pass Air through perpendicular and parallel. 2) Swirl Diffuser.:-     WHO permit or recommended diffuser used to pharma company. This type of diffuser use to air pass rotation flow. Diffuser pass Air through swirl rotary.